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What is leukaemia?

Leukaemias are cancers of the white blood cells, which begin in the bone marrow.
 
Leukaemias are grouped in two ways: the type of white blood cell affected – lymphoid or myeloid; and how quickly the disease develops and gets worse. Acute leukaemia appears suddenly and grows quickly while chronic leukaemia appears gradually and develops slowly over months to years.
 
This information refers to four types of leukaemia; acute lymphoblastic leukaemia (ALL), chronic lymphocytic leukaemia (CLL), acute myeloid leukaemia (AML) and chronic myeloid leukaemia (CML).
 
It is estimated that more than 5,200 people were diagnosed with leukaemia in 2023. The average age at diagnosis is 65 years old.

Leukaemia symptoms

Many people with leukaemia have no symptoms. The symptoms tend to be mild at first and worsen slowly.
 
The main symptoms include:
 
*tiredness and/or anaemia (pale complexion, weakness and breathlessness)
*repeated infections (mouth sores, sore throat, fevers, sweats, coughing, frequent passing of urine with irritation, infected cuts and scratches, and boils)
*increased bruising and bleeding.
 
Other less common symptoms include:
 
*bone pain
*swollen, tender gums
*skin rashes
*headaches
*vision problems
*vomiting
*enlarged lymph glands
*enlarged spleen that may cause pain or discomfort
*chest pains.

Who is at risk for leukemia?

For the specific types, there are different factors that can raise your risk of getting that type. Overall, your risk of leukemia goes up as you age. It is most common over age 60.

Leukemia Risk Factors

You can’t prevent leukemia, and scientists don’t know how to predict who will get it. But certain things might raise your risk of getting it. These include:
 
*Smoking. People who smoke or are around secondhand smoke are more likely to get a kind of leukemia called AML.
 
*Being around certain chemicals at work. People who work around chemicals such as benzene and formaldehyde have a higher risk of getting leukemia. People might also be exposed to harmful chemicals in the environment.
 
*Other cancer treatments. Sometimes, people who have had treatments such as radiation therapy or chemotherapy for other kinds of cancer might end up with leukemia.
 
*Some genetic conditions. People born with Down syndrome, Klinefelter syndrome, neurofibromatosis, or other conditions are more likely to get leukemia. If you have a condition that affects your leukemia risk, ask your doctor if there are any special tests or screenings you might need.
 
*Radiation. People who have been exposed to a lot of radiation are at higher risk of leukemia.
 
*Race. Your race and ethnicity can impact your risk of getting leukemia. For example, children who are Latino/a, Hispanic, or of Spanish descent are more likely than non-Latino kids to get leukemia. Research shows that people of Asian descent have a higher risk of getting acute myeloid leukemia (AML) but a lower risk of other leukemia types. People who are Black have a lower chance of getting most types of leukemia than people of other races.
 
*Gender. Males are a little bit more likely to get leukemia than females.
 
*Family history. If other people in your family have had leukemia, you might be more likely to get it.
 
*Age. Leukemia is more common in children and adults older than 55.
Sources and References
https://my.clevelandclinic.org/health/diseases/4365-leukemia#symptoms-and-causeshttps://www.cancer.org.au/cancer-information/types-of-cancer/leukaemiahttps://www.webmd.com/cancer/lymphoma/understanding-leukemia-basics#1-4https://medlineplus.gov/leukemia.html